loading...| Preferred Name | Methohexital | |
| Synonyms |
|
|
| Definitions |
A rapid, short-acting barbituric acid derivative, with anesthetic activity. Methohexital binds to the chloride ionophore site of the gamma-aminobutyric acid (GABA)-A/chloride ionophore receptor complex, thereby enhancing the inhibitory actions of GABA-A in the brain. This leads to synaptic inhibition, decreased neuronal excitability, and induction of anesthesia. In addition, this agent decreases glutamate (Glu) responses. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C66116 |
|
| CAS_Registry |
151-83-7 18652-93-2 |
|
| CHEBI_ID |
CHEBI:102216 |
|
| Chemical_Formula |
C14H18N2O3 |
|
| code |
C66116 |
|
| Contributing_Source |
FDA |
|
| definition |
A rapid, short-acting barbituric acid derivative, with anesthetic activity. Methohexital binds to the chloride ionophore site of the gamma-aminobutyric acid (GABA)-A/chloride ionophore receptor complex, thereby enhancing the inhibitory actions of GABA-A in the brain. This leads to synaptic inhibition, decreased neuronal excitability, and induction of anesthesia. In addition, this agent decreases glutamate (Glu) responses. |
|
| FDA_UNII_Code |
E5B8ND5IPE |
|
| in_subset | ||
| label |
Methohexital |
|
| Legacy Concept Name |
Methohexital |
|
| Preferred_Name |
Methohexital |
|
| prefixIRI |
NCIT:C66116 |
|
| prefLabel |
Methohexital |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0025668 |
|
| subClassOf |