Preferred Name |
Isoetharine |
|
Synonyms |
|
|
Definitions |
A beta-adrenergic receptor agonist with bronchodilator activity. Isoetharine selectively binds to beta-2 adrenergic receptors in bronchial smooth muscle, thereby activating intracellular adenyl cyclase, an enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP levels cause relaxation of bronchial smooth muscle, relieve bronchospasms, improve mucociliary clearance and reduce mediator substance release from inflammatory cells, especially from mast cells. |
|
ID |
http://purl.obolibrary.org/obo/NCIT_C65974 |
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CAS_Registry |
530-08-5 |
|
Chemical_Formula |
C13H21NO3 |
|
code |
C65974 |
|
Contributing_Source |
FDA |
|
definition |
A beta-adrenergic receptor agonist with bronchodilator activity. Isoetharine selectively binds to beta-2 adrenergic receptors in bronchial smooth muscle, thereby activating intracellular adenyl cyclase, an enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP levels cause relaxation of bronchial smooth muscle, relieve bronchospasms, improve mucociliary clearance and reduce mediator substance release from inflammatory cells, especially from mast cells. |
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FDA_UNII_Code |
YV0SN3276Q |
|
Has_Salt_Form | ||
in_subset | ||
label |
Isoetharine |
|
Legacy Concept Name |
Isoetharine |
|
Preferred_Name |
Isoetharine |
|
prefixIRI |
NCIT:C65974 |
|
prefLabel |
Isoetharine |
|
Semantic_Type |
Pharmacologic Substance |
|
UMLS_CUI |
C0022176 |
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subClassOf |