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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Cefpodoxime | |
| Synonyms |
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| Definitions |
A third generation semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity. Cefpodoxime's effect is dependent on its binding to penicillin-binding proteins (PBPs) located in the bacterial cytoplasmic membrane. Binding results in the inhibition of the transpeptidase enzymes, thereby preventing cross-linking of the pentaglycine bridge with the fourth residue of the pentapeptide and interrupting consequent synthesis of peptidoglycan chains. As a result, cefpodoxime inhibits bacterial septum and cell wall synthesis formation. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C65305 |
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| CAS_Registry |
80210-62-4
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| CHEBI_ID |
CHEBI:3504
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| Chemical_Formula |
C15H17N5O6S2
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|
| code |
C65305
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| Contributing_Source |
FDA
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|
| definition |
A third generation semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity. Cefpodoxime's effect is dependent on its binding to penicillin-binding proteins (PBPs) located in the bacterial cytoplasmic membrane. Binding results in the inhibition of the transpeptidase enzymes, thereby preventing cross-linking of the pentaglycine bridge with the fourth residue of the pentapeptide and interrupting consequent synthesis of peptidoglycan chains. As a result, cefpodoxime inhibits bacterial septum and cell wall synthesis formation.
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| FDA_UNII_Code |
7R4F94TVGY
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| in_subset | ||
| label |
Cefpodoxime
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|
| Legacy Concept Name |
Cefpodoxime_Base
|
|
| Preferred_Name |
Cefpodoxime
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|
| prefixIRI |
NCIT:C65305
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| prefLabel |
Cefpodoxime
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| Semantic_Type |
Pharmacologic Substance
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| UMLS_CUI |
C0055011
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| subClassOf |
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