Biological and Environmental Research Ontology

Last uploaded: December 23, 2022
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Preferred Name

Metolazone
Synonyms
Definitions

A long acting, quinazoline-based sulfonamide thiazide-like, diuretic. Similar to the thiazides, metolazone acts on the distal convoluted tubule (DCT) and inhibits the sodium-chloride symporter, thereby preventing sodium and chloride reabsorption and excretion of water.
ID

http://purl.obolibrary.org/obo/NCIT_C650
CAS_Registry

17560-51-9
CHEBI_ID

CHEBI:64354
Chemical_Formula

C16H16ClN3O3S
code

C650
Contributing_Source

FDA
definition

A long acting, quinazoline-based sulfonamide thiazide-like, diuretic. Similar to the thiazides, metolazone acts on the distal convoluted tubule (DCT) and inhibits the sodium-chloride symporter, thereby preventing sodium and chloride reabsorption and excretion of water.
FDA_UNII_Code

TZ7V40X7VX
in_subset

http://purl.obolibrary.org/obo/NCIT_C63923
label

Metolazone
Legacy Concept Name

Metolazone
Preferred_Name

Metolazone
prefixIRI

NCIT:C650
prefLabel

Metolazone
Semantic_Type

Organic Chemical

Pharmacologic Substance
UMLS_CUI

C0025854
subClassOf

http://purl.obolibrary.org/obo/NCIT_C49185
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http://purl.obolibrary.org/obo/CHEBI_64354 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_64354 CHEBI LOOM
http://purl.bioontology.org/ontology/LNC/LP17954-6 LOINC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D008788 RH-MESH LOOM
http://www.co-ode.org/ontologies/galen#Metolazone GALEN LOOM
http://purl.obolibrary.org/obo/OMIT_0009844 OMIT LOOM
http://purl.bioontology.org/ontology/SNMI/C-72290 SNMI LOOM
http://purl.obolibrary.org/obo/CHEBI_64354 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_64354 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_64354 DRON LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0025854 OCHV LOOM
http://purl.jp/bio/4/id/200906012553796770 IOBC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#8070 OCHV LOOM
http://www.phoc.org.cn/pmo/class/PMO_00015958 PMAPP-PMO LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000146498 ODAE LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000146498 KTAO LOOM
http://purl.bioontology.org/ontology/MESH/D008788 MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.886.590.700.600 RH-MESH LOOM
http://purl.bioontology.org/ontology/LNC/MTHU060443 LOINC LOOM
http://purl.bioontology.org/ontology/VANDF/4018161 VANDF LOOM
http://bmi.utah.edu/ontologies/hfontology/C0025854 HFO LOOM
http://www.drugbank.ca/drugs/DB00524 FTC LOOM
http://stirdf.jst.go.jp/id/200907052666475291 IOBC LOOM
http://purl.bioontology.org/ontology/RXNORM/6916 RXNORM LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146498 NDFRT LOOM
http://purl.bioontology.org/ontology/ATC/C03BA08 ATC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.438.786.830.688 RH-MESH LOOM
http://purl.obolibrary.org/obo/DRON_00015990 ODNAE LOOM
http://purl.bioontology.org/ontology/RCD/b2b.. RCD LOOM
https://go.drugbank.com/drugs/DB00524 MDM LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C650 NCIT LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387123003 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/NDDF/002310 NDDF LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.065.884.600 RH-MESH LOOM