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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Sodium Citrate | |
| Synonyms |
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| Definitions |
The sodium salt of citrate with alkalinizing activity. Upon absorption, sodium citrate dissociates into sodium cations and citrate anions; organic citrate ions are metabolized to bicarbonate ions, resulting in an increase in the plasma bicarbonate concentration, the buffering of excess hydrogen ion, the raising of blood pH, and potentially the reversal of acidosis. In addition, increases in free sodium load due to sodium citrate administration may increase intravascular blood volume, facilitating the excretion of bicarbonate compounds and an anti-urolithic effect. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C62075 |
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| ALT_DEFINITION |
A drug used in the treatment of metabolic acidosis (a disorder in which the blood is too acidic).
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| CAS_Registry |
6132-04-3
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| CHEBI_ID |
CHEBI:32142
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| code |
C62075
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| Contributing_Source |
FDA
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| definition |
The sodium salt of citrate with alkalinizing activity. Upon absorption, sodium citrate dissociates into sodium cations and citrate anions; organic citrate ions are metabolized to bicarbonate ions, resulting in an increase in the plasma bicarbonate concentration, the buffering of excess hydrogen ion, the raising of blood pH, and potentially the reversal of acidosis. In addition, increases in free sodium load due to sodium citrate administration may increase intravascular blood volume, facilitating the excretion of bicarbonate compounds and an anti-urolithic effect.
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| FDA_UNII_Code |
1Q73Q2JULR
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| in_subset | ||
| label |
Sodium Citrate
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| Legacy Concept Name |
Sodium_Citrate
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| NCI_Drug_Dictionary_ID |
361795
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| PDQ_Closed_Trial_Search_ID |
361795
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| PDQ_Open_Trial_Search_ID |
361795
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|
| Preferred_Name |
Sodium Citrate
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|
| prefixIRI |
NCIT:C62075
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| prefLabel |
Sodium Citrate
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| Semantic_Type |
Organic Chemical Pharmacologic Substance
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| UMLS_CUI |
C0142825
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| subClassOf |
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