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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Hydrocodone | |
| Synonyms |
|
|
| Definitions |
A semisynthetic hydrogenated codeine derivative and opioid agonist with analgesic and antitussive effects. Hydrocodone primarily binds to and activates the mu-opioid receptor in the central nervous system (CNS). This leads to analgesia, euphoria, respiratory depression, miosis, decreased gastrointestinal motility, cough suppression and physical dependence. Hydrocodone is converted to hydromorphone by the cytochrome P450 enzyme CYP2D6. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C62033 |
|
| CAS_Registry |
125-29-1
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|
| CHEBI_ID |
CHEBI:5779
|
|
| Chemical_Formula |
C18H21NO3
|
|
| code |
C62033
|
|
| Contributing_Source |
CTRP FDA
|
|
| definition |
A semisynthetic hydrogenated codeine derivative and opioid agonist with analgesic and antitussive effects. Hydrocodone primarily binds to and activates the mu-opioid receptor in the central nervous system (CNS). This leads to analgesia, euphoria, respiratory depression, miosis, decreased gastrointestinal motility, cough suppression and physical dependence. Hydrocodone is converted to hydromorphone by the cytochrome P450 enzyme CYP2D6.
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|
| Display_Name |
Hydrocodone
|
|
| FDA_UNII_Code |
6YKS4Y3WQ7
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|
| Has_Salt_Form | ||
| Has_Target | ||
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 |
|
| label |
Hydrocodone
|
|
| Legacy Concept Name |
Hydrocodone_Base
|
|
| Preferred_Name |
Hydrocodone
|
|
| prefixIRI |
NCIT:C62033
|
|
| prefLabel |
Hydrocodone
|
|
| Semantic_Type |
Pharmacologic Substance
|
|
| UMLS_CUI |
C0020264
|
|
| subClassOf |
http://purl.obolibrary.org/obo/NCIT_C66917 |
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