Preferred Name |
Granisetron |
|
Synonyms |
|
|
Definitions |
An indazole derivative with antiemetic properties. As a selective serotonin receptor antagonist, granisetron competitively blocks the action of serotonin at 5-hydroxytryptamine3 (5-HT3) receptors, resulting in the suppression of chemotherapy- and radiotherapy-induced nausea and vomiting. |
|
ID |
http://purl.obolibrary.org/obo/NCIT_C62031 |
|
Accepted_Therapeutic_Use_For |
Chemotherapy induced nausea or vomiting |
|
ALT_DEFINITION |
The active ingredient in a drug used to treat nausea and vomiting caused by cancer treatment. Granisetron is a type of serotonin receptor antagonist and a type of antiemetic. |
|
CAS_Registry |
109889-09-0 |
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Chemical_Formula |
C18H24N4O |
|
code |
C62031 |
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Contributing_Source |
FDA |
|
definition |
An indazole derivative with antiemetic properties. As a selective serotonin receptor antagonist, granisetron competitively blocks the action of serotonin at 5-hydroxytryptamine3 (5-HT3) receptors, resulting in the suppression of chemotherapy- and radiotherapy-induced nausea and vomiting. |
|
FDA_UNII_Code |
WZG3J2MCOL |
|
Has_Salt_Form | ||
in_subset | ||
label |
Granisetron |
|
Legacy Concept Name |
Granisetron_Base |
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NCI_Drug_Dictionary_ID |
794007 |
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PDQ_Closed_Trial_Search_ID |
794007 |
|
PDQ_Open_Trial_Search_ID |
794007 |
|
Preferred_Name |
Granisetron |
|
prefixIRI |
NCIT:C62031 |
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prefLabel |
Granisetron |
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Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
UMLS_CUI |
C0061863 |
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subClassOf |