Preferred Name |
Ticlopidine |
|
Synonyms |
|
|
Definitions |
A thienopyridine derivative with anticoagulant activity. Ticlopidine inhibits adenosine-diphosphate (ADP) binding to its platelet receptor. This prevents ADP activation and inhibits platelet expression of the glycoprotein (GP) IIb/IIIA receptors, binding of fibrinogen to platelet glycoprotein GP IIb-IIIa and platelet-platelet interaction. This results in increased bleeding time. |
|
ID |
http://purl.obolibrary.org/obo/NCIT_C61972 |
|
CAS_Registry |
55142-85-3 |
|
CHEBI_ID |
CHEBI:9588 |
|
Chemical_Formula |
C14H14ClNS |
|
code |
C61972 |
|
Contributing_Source |
FDA |
|
definition |
A thienopyridine derivative with anticoagulant activity. Ticlopidine inhibits adenosine-diphosphate (ADP) binding to its platelet receptor. This prevents ADP activation and inhibits platelet expression of the glycoprotein (GP) IIb/IIIA receptors, binding of fibrinogen to platelet glycoprotein GP IIb-IIIa and platelet-platelet interaction. This results in increased bleeding time. |
|
FDA_UNII_Code |
OM90ZUW7M1 |
|
Has_Salt_Form | ||
in_subset | ||
label |
Ticlopidine |
|
Legacy Concept Name |
Ticlopidine |
|
Preferred_Name |
Ticlopidine |
|
prefixIRI |
NCIT:C61972 |
|
prefLabel |
Ticlopidine |
|
Semantic_Type |
Pharmacologic Substance |
|
UMLS_CUI |
C0040207 |
|
subClassOf |