Preferred Name

Succimer
Synonyms
Definitions

An orally active mercaptodicarboxylic acid, with heavy metal chelating activity. As a strong chelator, succimer is able to bind to heavy metals, such as lead, in the bloodstream, thereby forming a water-soluble complex that can be eliminated via urinary excretion. This prevents heavy metal poisoning. In addition, succimer is able to chelate the alpha particle emitter and radionuclide polonium Po 210 ((Po-210), thereby increasing its excretion and reducing the toxic effects of Po-210.

ID

http://purl.obolibrary.org/obo/NCIT_C61953

CAS_Registry

304-55-2

CHEBI_ID

CHEBI:63623

Chemical_Formula

C4H6O4S2

code

C61953

Contributing_Source

CTRP

FDA

definition

An orally active mercaptodicarboxylic acid, with heavy metal chelating activity. As a strong chelator, succimer is able to bind to heavy metals, such as lead, in the bloodstream, thereby forming a water-soluble complex that can be eliminated via urinary excretion. This prevents heavy metal poisoning. In addition, succimer is able to chelate the alpha particle emitter and radionuclide polonium Po 210 ((Po-210), thereby increasing its excretion and reducing the toxic effects of Po-210.

Display_Name

Succimer

FDA_UNII_Code

DX1U2629QE

in_subset

http://purl.obolibrary.org/obo/NCIT_C63923

http://purl.obolibrary.org/obo/NCIT_C176424

http://purl.obolibrary.org/obo/NCIT_C116977

http://purl.obolibrary.org/obo/NCIT_C116978

label

Succimer

Legacy Concept Name

Succimer

NCI_Drug_Dictionary_ID

798947

PDQ_Closed_Trial_Search_ID

798947

PDQ_Open_Trial_Search_ID

798947

Preferred_Name

Succimer

prefixIRI

NCIT:C61953

prefLabel

Succimer

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0012384

subClassOf

http://purl.obolibrary.org/obo/NCIT_C360

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Delete Mapping To Ontology Source
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D004113 RH-MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0012384 OCHV LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.241.081.337.759.500 RH-MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#3962 OCHV LOOM
http://purl.bioontology.org/ontology/MESH/D004113 MESH LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147417 NDFRT LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/109104002 SNOMEDCT LOOM
http://purl.obolibrary.org/obo/dinto_DB00566 DINTO LOOM
http://purl.bioontology.org/ontology/VANDF/4019174 VANDF LOOM
http://purl.obolibrary.org/obo/CHEBI_63623 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_63623 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_63623 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_63623 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_63623 DRON LOOM
http://purl.obolibrary.org/obo/DRON_00011589 ODNAE LOOM
http://purl.bioontology.org/ontology/NDDF/003583 NDDF LOOM
https://go.drugbank.com/drugs/DB00566 MDM LOOM
http://www.phoc.org.cn/pmo/class/PMO_00016404 PMAPP-PMO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.886.489.750 RH-MESH LOOM
http://purl.obolibrary.org/obo/OMIT_0005378 OMIT LOOM
http://purl.bioontology.org/ontology/RXNORM/3446 RXNORM LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000147417 ODAE LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61953 ENM LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61953 NCIT LOOM