Preferred Name

Procaine

Synonyms
Definitions

A benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodium channels, thereby inhibiting the ionic flux required for the initiation and conduction of impulses. In addition, this agent increases electrical excitation threshold, reduces rate of rise of action potential and slows nerve impulse propagation thereby causing loss of sensation.

ID

http://purl.obolibrary.org/obo/NCIT_C61906

CAS_Registry

59-46-1

CHEBI_ID

CHEBI:8430

Chemical_Formula

C13H20N2O2

code

C61906

Contributing_Source

FDA

definition

A benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodium channels, thereby inhibiting the ionic flux required for the initiation and conduction of impulses. In addition, this agent increases electrical excitation threshold, reduces rate of rise of action potential and slows nerve impulse propagation thereby causing loss of sensation.

FDA_UNII_Code

4Z8Y51M438

Has_Salt_Form

http://purl.obolibrary.org/obo/NCIT_C97301

http://purl.obolibrary.org/obo/NCIT_C132291

http://purl.obolibrary.org/obo/NCIT_C47688

in_subset

http://purl.obolibrary.org/obo/NCIT_C63923

label

Procaine

Legacy Concept Name

Procaine

Preferred_Name

Procaine

prefixIRI

NCIT:C61906

prefLabel

Procaine

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0033218

subClassOf

http://purl.obolibrary.org/obo/NCIT_C245

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http://purl.obolibrary.org/obo/OMIT_0012299 OMIT LOOM
http://purl.bioontology.org/ontology/ATC/S01HA05 ATC LOOM
http://purl.bioontology.org/ontology/MESH/D011343 MESH LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387238009 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/SNMI/C-6B070 SNMI LOOM
https://go.drugbank.com/drugs/DB00721 MDM LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#10138 OCHV LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.241.223.100.050.500.906 RH-MESH LOOM
http://purl.bioontology.org/ontology/ATC/C05AD05 ATC LOOM
http://www.drugbank.ca/drugs/DB00721 FTC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.426.559.389.127.020.937.906 RH-MESH LOOM
http://purl.bioontology.org/ontology/LNC/MTHU003046 LOINC LOOM
http://purl.bioontology.org/ontology/NDDF/004565 NDDF LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61906 NCIT LOOM
http://purl.obolibrary.org/obo/CHEBI_8430 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_8430 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_8430 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_8430 OBIB LOOM
http://purl.obolibrary.org/obo/CHEBI_8430 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_8430 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_8430 NIFSTD LOOM
http://purl.jp/bio/4/id/200906046832175834 IOBC LOOM
http://purl.bioontology.org/ontology/ATC/N01BA02 ATC LOOM
http://purl.bioontology.org/ontology/RXNORM/8701 RXNORM LOOM
http://www.phoc.org.cn/pmo/class/PMO_00016495 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/VANDF/4019905 VANDF LOOM
http://purl.bioontology.org/ontology/LNC/LP17981-9 LOINC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0033218 OCHV LOOM
http://www.co-ode.org/ontologies/galen#Procaine GALEN LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147990 NDFRT LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Procaine APAONTO LOOM
http://purl.bioontology.org/ontology/RCD/X79Gw RCD LOOM
http://purl.bioontology.org/ontology/CSP/0129-0497 CRISP LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D011343 RH-MESH LOOM
http://stirdf.jst.go.jp/id/200907067942726284 IOBC LOOM