loading...| Preferred Name |
Imipramine Pamoate |
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| Synonyms |
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| Definitions |
The pamoate salt of imipramine, a synthetic dibenzazepine derivative with anti-depressant activity. Imipramine pamoate, a tricyclic antidepressant (TCA) potentiates the activity of adrenergic synapses by blocking the re-uptake of norepinephrine and serotonin, thereby preventing their degradation and increasing their availability. This drug also has antimuscarinic and anti-histamine properties, which contribute to its side effects. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C61788 |
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| CAS_Registry |
10075-24-8 22540-17-6 |
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| Chemical_Formula |
C23H16O6.2C19H24N2 |
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| code |
C61788 |
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| Contributing_Source |
FDA |
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| definition |
The pamoate salt of imipramine, a synthetic dibenzazepine derivative with anti-depressant activity. Imipramine pamoate, a tricyclic antidepressant (TCA) potentiates the activity of adrenergic synapses by blocking the re-uptake of norepinephrine and serotonin, thereby preventing their degradation and increasing their availability. This drug also has antimuscarinic and anti-histamine properties, which contribute to its side effects. |
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| FDA_UNII_Code |
MC34P30298 |
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| Has_Free_Acid_Or_Base_Form | ||
| in_subset | ||
| label |
Imipramine Pamoate |
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| Legacy Concept Name |
Imipramine_Pamoate |
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| Preferred_Name |
Imipramine Pamoate |
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| prefixIRI |
NCIT:C61788 |
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| prefLabel |
Imipramine Pamoate |
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| Semantic_Type |
Pharmacologic Substance |
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| UMLS_CUI |
C0304368 |
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| subClassOf |