Link to this page
Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
Jump to:
| Preferred Name | Guanfacine | |
| Synonyms |
|
|
| Definitions |
A centrally acting adrenergic agonist with non-stimulant and antihypertensive property. Guanfacine selectively stimulates alpha-2 adrenergic receptors in the central nervous system, thereby resulting in inhibition of sympathetic nervous system outflow. Used alone or in combination with other drugs, this agent causes reduction of peripheral and renal vascular resistance, and lowers both systolic and diastolic blood pressure and heart rate. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C61779 |
|
| CAS_Registry |
29110-47-2
|
|
| Chemical_Formula |
C9H9Cl2N3O
|
|
| code |
C61779
|
|
| Contributing_Source |
FDA
|
|
| definition |
A centrally acting adrenergic agonist with non-stimulant and antihypertensive property. Guanfacine selectively stimulates alpha-2 adrenergic receptors in the central nervous system, thereby resulting in inhibition of sympathetic nervous system outflow. Used alone or in combination with other drugs, this agent causes reduction of peripheral and renal vascular resistance, and lowers both systolic and diastolic blood pressure and heart rate.
|
|
| FDA_UNII_Code |
30OMY4G3MK
|
|
| Has_Salt_Form | ||
| in_subset | ||
| label |
Guanfacine
|
|
| Legacy Concept Name |
Guanfacine
|
|
| Preferred_Name |
Guanfacine
|
|
| prefixIRI |
NCIT:C61779
|
|
| prefLabel |
Guanfacine
|
|
| Semantic_Type |
Pharmacologic Substance
|
|
| UMLS_CUI |
C0079466
|
|
| subClassOf |
Add comment
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |
Create mapping