loading...| Preferred Name | Doxapram | |
| Synonyms |
|
|
| Definitions |
A respiratory stimulant with analeptic activity. Doxapram, independent of oxygen levels, directly stimulates the peripheral carotid chemoreceptors, possibly by inhibiting the potassium channels of type I cells within the carotid body, thereby stimulating catecholamines release. This results in the prevention or reversal of both narcotic- and CNS depressant-induced respiratory depression. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C61736 |
|
| CAS_Registry |
309-29-5 |
|
| CHEBI_ID |
CHEBI:681848 |
|
| Chemical_Formula |
C24H30N2O2 |
|
| code |
C61736 |
|
| Contributing_Source |
FDA |
|
| definition |
A respiratory stimulant with analeptic activity. Doxapram, independent of oxygen levels, directly stimulates the peripheral carotid chemoreceptors, possibly by inhibiting the potassium channels of type I cells within the carotid body, thereby stimulating catecholamines release. This results in the prevention or reversal of both narcotic- and CNS depressant-induced respiratory depression. |
|
| FDA_UNII_Code |
94F3830Q73 |
|
| Has_Salt_Form | ||
| in_subset | ||
| label |
Doxapram |
|
| Legacy Concept Name |
Doxapram |
|
| Preferred_Name |
Doxapram |
|
| prefixIRI |
NCIT:C61736 |
|
| prefLabel |
Doxapram |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0013084 |
|
| subClassOf |