Preferred Name

Dexchlorpheniramine

Synonyms
Definitions

An alkylamine, and first-generation histamine antagonist with anti-allergic activity. Dexchlorpheniramine competitively blocks H1 receptors, thereby preventing the actions of histamine on bronchial smooth muscle, capillaries and gastrointestinal (GI) smooth muscle. The antagonistic action of this agent blocks the activities of endogenous histamine, thereby preventing histamine-induced bronchoconstriction, vasodilation, increased capillary permeability, and GI smooth muscle spasms.

ID

http://purl.obolibrary.org/obo/NCIT_C61707

CAS_Registry

25523-97-1

CHEBI_ID

CHEBI:4464

Chemical_Formula

C16H19ClN2

code

C61707

Contributing_Source

FDA

definition

An alkylamine, and first-generation histamine antagonist with anti-allergic activity. Dexchlorpheniramine competitively blocks H1 receptors, thereby preventing the actions of histamine on bronchial smooth muscle, capillaries and gastrointestinal (GI) smooth muscle. The antagonistic action of this agent blocks the activities of endogenous histamine, thereby preventing histamine-induced bronchoconstriction, vasodilation, increased capillary permeability, and GI smooth muscle spasms.

FDA_UNII_Code

3Q9Q0B929N

Has_Salt_Form

http://purl.obolibrary.org/obo/NCIT_C47478

in_subset

http://purl.obolibrary.org/obo/NCIT_C63923

label

Dexchlorpheniramine

Legacy Concept Name

Dexchlorpheniramine

Preferred_Name

Dexchlorpheniramine

prefixIRI

NCIT:C61707

prefLabel

Dexchlorpheniramine

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0057606

subClassOf

http://purl.obolibrary.org/obo/NCIT_C29578

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