Preferred Name

Dexbrompheniramine

Synonyms
Definitions

An alkylamine derivative with anticholinergic and sedative properties. Dexbrompheniramine is a histamine H1-receptor antagonist that competes with histamine for the H1-receptor sites on effector cells in the gastrointestinal tract, blood vessels and respiratory tract. The antagonistic action of this agent blocks the activities of endogenous histamine, which subsequently leads to temporary relief from the negative histamine-mediated symptoms of allergic reaction such as bronchoconstriction, vasodilation, increased capillary permeability and spasmodic contractions of gastrointestinal smooth muscle.

ID

http://purl.obolibrary.org/obo/NCIT_C61705

CAS_Registry

132-21-8

CHEBI_ID

CHEBI:59269

Chemical_Formula

C16H19BrN2

code

C61705

Contributing_Source

FDA

definition

An alkylamine derivative with anticholinergic and sedative properties. Dexbrompheniramine is a histamine H1-receptor antagonist that competes with histamine for the H1-receptor sites on effector cells in the gastrointestinal tract, blood vessels and respiratory tract. The antagonistic action of this agent blocks the activities of endogenous histamine, which subsequently leads to temporary relief from the negative histamine-mediated symptoms of allergic reaction such as bronchoconstriction, vasodilation, increased capillary permeability and spasmodic contractions of gastrointestinal smooth muscle.

FDA_UNII_Code

75T64B71RP

Has_Salt_Form

http://purl.obolibrary.org/obo/NCIT_C61706

in_subset

http://purl.obolibrary.org/obo/NCIT_C63923

label

Dexbrompheniramine

Legacy Concept Name

Dexbrompheniramine

Preferred_Name

Dexbrompheniramine

prefixIRI

NCIT:C61705

prefLabel

Dexbrompheniramine

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0057605

subClassOf

http://purl.obolibrary.org/obo/NCIT_C29578

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