Biological and Environmental Research Ontology

Last uploaded: December 23, 2022
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Preferred Name

Dexbrompheniramine
Synonyms
Definitions

An alkylamine derivative with anticholinergic and sedative properties. Dexbrompheniramine is a histamine H1-receptor antagonist that competes with histamine for the H1-receptor sites on effector cells in the gastrointestinal tract, blood vessels and respiratory tract. The antagonistic action of this agent blocks the activities of endogenous histamine, which subsequently leads to temporary relief from the negative histamine-mediated symptoms of allergic reaction such as bronchoconstriction, vasodilation, increased capillary permeability and spasmodic contractions of gastrointestinal smooth muscle.
ID

http://purl.obolibrary.org/obo/NCIT_C61705
CAS_Registry

132-21-8
CHEBI_ID

CHEBI:59269
Chemical_Formula

C16H19BrN2
code

C61705
Contributing_Source

FDA
definition

An alkylamine derivative with anticholinergic and sedative properties. Dexbrompheniramine is a histamine H1-receptor antagonist that competes with histamine for the H1-receptor sites on effector cells in the gastrointestinal tract, blood vessels and respiratory tract. The antagonistic action of this agent blocks the activities of endogenous histamine, which subsequently leads to temporary relief from the negative histamine-mediated symptoms of allergic reaction such as bronchoconstriction, vasodilation, increased capillary permeability and spasmodic contractions of gastrointestinal smooth muscle.
FDA_UNII_Code

75T64B71RP
Has_Salt_Form

http://purl.obolibrary.org/obo/NCIT_C61706
in_subset

http://purl.obolibrary.org/obo/NCIT_C63923
label

Dexbrompheniramine
Legacy Concept Name

Dexbrompheniramine
Preferred_Name

Dexbrompheniramine
prefixIRI

NCIT:C61705
prefLabel

Dexbrompheniramine
Semantic_Type

Pharmacologic Substance
UMLS_CUI

C0057605
subClassOf

http://purl.obolibrary.org/obo/NCIT_C29578
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