loading...| Preferred Name |
Ciclopirox |
|
| Synonyms |
|
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| Definitions |
A synthetic, broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities. Ciclopirox exerts its action by binding to and chelating trivalent cations, such as Fe3+ and Al3+, thereby inhibiting the availability of essential co-factors for enzymes. This may lead to a loss of activity of enzymes that are essential for cellular metabolism, organization of cell wall structure and other crucial cell functions. In addition, ciclopirox exerts its anti-inflammatory activity by inhibiting 5-lipoxygenase and cyclooxygenase (COX). |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C61677 |
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| CAS_Registry |
29342-05-0 |
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| CHEBI_ID |
CHEBI:453011 |
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| Chemical_Formula |
C12H17NO2 |
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| code |
C61677 |
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| Contributing_Source |
FDA |
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| definition |
A synthetic, broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities. Ciclopirox exerts its action by binding to and chelating trivalent cations, such as Fe3+ and Al3+, thereby inhibiting the availability of essential co-factors for enzymes. This may lead to a loss of activity of enzymes that are essential for cellular metabolism, organization of cell wall structure and other crucial cell functions. In addition, ciclopirox exerts its anti-inflammatory activity by inhibiting 5-lipoxygenase and cyclooxygenase (COX). |
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| FDA_UNII_Code |
19W019ZDRJ |
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| Has_Salt_Form | ||
| in_subset | ||
| label |
Ciclopirox |
|
| Legacy Concept Name |
Ciclopirox |
|
| Preferred_Name |
Ciclopirox |
|
| prefixIRI |
NCIT:C61677 |
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| prefLabel |
Ciclopirox |
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| Semantic_Type |
Pharmacologic Substance |
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| UMLS_CUI |
C0055711 |
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| subClassOf |