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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Cefotetan | |
| Synonyms |
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| Definitions |
A semi-synthetic, broad-spectrum, beta-lactamase-resistant, second-generation cephalosporin antibiotic derived from cephalosporium. The bactericidal activity of cefotetan disodium is caused by an inhibition of bacterial cell wall synthesis via inhibition of cross-linking of peptidoglycans. This results in a reduction of cell wall stability and causes cell lysis. Cefotetan disodium is more active against gram-negative organisms and less active against gram-positive organisms compared to first-generation cephalosporins. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C61664 |
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| CAS_Registry |
69712-56-7
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|
| CHEBI_ID |
CHEBI:3499
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| Chemical_Formula |
C17H17N7O8S4
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| code |
C61664
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| Contributing_Source |
FDA
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|
| definition |
A semi-synthetic, broad-spectrum, beta-lactamase-resistant, second-generation cephalosporin antibiotic derived from cephalosporium. The bactericidal activity of cefotetan disodium is caused by an inhibition of bacterial cell wall synthesis via inhibition of cross-linking of peptidoglycans. This results in a reduction of cell wall stability and causes cell lysis. Cefotetan disodium is more active against gram-negative organisms and less active against gram-positive organisms compared to first-generation cephalosporins.
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| FDA_UNII_Code |
48SPP0PA9Q
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| Has_Salt_Form | ||
| in_subset | ||
| label |
Cefotetan
|
|
| Legacy Concept Name |
Cefotetan
|
|
| Preferred_Name |
Cefotetan
|
|
| prefixIRI |
NCIT:C61664
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|
| prefLabel |
Cefotetan
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| Semantic_Type |
Pharmacologic Substance
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| UMLS_CUI |
C0007555
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| subClassOf |
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