loading...| Preferred Name |
Alfentanil |
|
| Synonyms |
|
|
| Definitions |
A synthetic short-acting opioid with analgesic and local anesthesia enhancing activity. Alfentanil primarily binds to mu-opioid receptor, a G-protein-coupled receptor, thereby mimicking the actions of morphine, the prototypical mu receptor agonist. This agent induces anti-nociception responses mediated through inhibiting the release of various neurotransmitters such as substance P, GABA, dopamine, acetylcholine and noradrenaline; in addition, the release of vasopressin, somatostatin, insulin and glucagon are also inhibited. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C61626 |
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| CAS_Registry |
71195-58-9 |
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| CHEBI_ID |
CHEBI:2569 |
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| Chemical_Formula |
C21H32N6O3 |
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| code |
C61626 |
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| Contributing_Source |
FDA |
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| definition |
A synthetic short-acting opioid with analgesic and local anesthesia enhancing activity. Alfentanil primarily binds to mu-opioid receptor, a G-protein-coupled receptor, thereby mimicking the actions of morphine, the prototypical mu receptor agonist. This agent induces anti-nociception responses mediated through inhibiting the release of various neurotransmitters such as substance P, GABA, dopamine, acetylcholine and noradrenaline; in addition, the release of vasopressin, somatostatin, insulin and glucagon are also inhibited. |
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| FDA_UNII_Code |
1N74HM2BS7 |
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| Has_Salt_Form | ||
| in_subset | ||
| label |
Alfentanil |
|
| Legacy Concept Name |
Alfentanil |
|
| Preferred_Name |
Alfentanil |
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| prefixIRI |
NCIT:C61626 |
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| prefLabel |
Alfentanil |
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| Semantic_Type |
Pharmacologic Substance |
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| UMLS_CUI |
C0002026 |
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| subClassOf |