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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Clomiphene | |
| Synonyms |
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| Definitions |
A triphenylethylene nonsteroidal ovulatory stimulant evaluated for antineoplastic activity against breast cancer. Clomiphene has both estrogenic and anti-estrogenic activities that compete with estrogen for binding at estrogen receptor sites in target tissues. This agent causes the release of the pituitary gonadotropins follicle stimulating hormone (FSH) and luteinizing hormone (LH), leading to ovulation. (NCI04) |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C61607 |
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| CAS_Registry |
911-45-5
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| CHEBI_ID |
CHEBI:3752
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| code |
C61607
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| Contributing_Source |
FDA
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| definition |
A triphenylethylene nonsteroidal ovulatory stimulant evaluated for antineoplastic activity against breast cancer. Clomiphene has both estrogenic and anti-estrogenic activities that compete with estrogen for binding at estrogen receptor sites in target tissues. This agent causes the release of the pituitary gonadotropins follicle stimulating hormone (FSH) and luteinizing hormone (LH), leading to ovulation. (NCI04)
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| FDA_UNII_Code |
1HRS458QU2
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| Has_Salt_Form | ||
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C128784 |
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| Is_Value_For_GDC_Property | ||
| label |
Clomiphene
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|
| Legacy Concept Name |
Clomiphene_Base
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| Maps_To |
Clomiphene
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| Preferred_Name |
Clomiphene
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| prefixIRI |
NCIT:C61607
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| prefLabel |
Clomiphene
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| Semantic_Type |
Organic Chemical Pharmacologic Substance
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| UMLS_CUI |
C0009008
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| subClassOf |
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