Preferred Name |
Levamisole Hydrochloride |
|
Synonyms |
|
|
Definitions |
The hydrochloride salt of the synthetic imidazothiazole derivative levamisole with anthelminthic and immunomodulating activities. In immunosuppressed states, levamisole may restore immune function by: 1) stimulating antibody formation, 2) stimulating T-cell activation and proliferation, 3) potentiating monocyte and macrophage phagocytosis and chemotaxis and 4) increasing neutrophil mobility, adherence, and chemotaxis. |
|
ID |
http://purl.obolibrary.org/obo/NCIT_C610 |
|
Accepted_Therapeutic_Use_For |
Stage III Colon Cancer |
|
CAS_Registry |
16595-80-5 |
|
Chemical_Formula |
C11H12N2S.HCl |
|
code |
C610 |
|
Contributing_Source |
CTRP FDA |
|
definition |
The hydrochloride salt of the synthetic imidazothiazole derivative levamisole with anthelminthic and immunomodulating activities. In immunosuppressed states, levamisole may restore immune function by: 1) stimulating antibody formation, 2) stimulating T-cell activation and proliferation, 3) potentiating monocyte and macrophage phagocytosis and chemotaxis and 4) increasing neutrophil mobility, adherence, and chemotaxis. |
|
Display_Name |
Levamisole Hydrochloride |
|
FDA_UNII_Code |
DL9055K809 |
|
Has_Free_Acid_Or_Base_Form | ||
in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C176424 |
|
label |
Levamisole Hydrochloride |
|
Legacy Concept Name |
Levamisole |
|
NCI_Drug_Dictionary_ID |
39058 |
|
NSC Number |
177023 |
|
PDQ_Closed_Trial_Search_ID |
39058 |
|
PDQ_Open_Trial_Search_ID |
39058 |
|
Preferred_Name |
Levamisole Hydrochloride |
|
prefixIRI |
NCIT:C610 |
|
prefLabel |
Levamisole Hydrochloride |
|
Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
UMLS_CUI |
C0733383 |
|
subClassOf |