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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Levamisole Hydrochloride | |
| Synonyms |
|
|
| Definitions |
The hydrochloride salt of the synthetic imidazothiazole derivative levamisole with anthelminthic and immunomodulating activities. In immunosuppressed states, levamisole may restore immune function by: 1) stimulating antibody formation, 2) stimulating T-cell activation and proliferation, 3) potentiating monocyte and macrophage phagocytosis and chemotaxis and 4) increasing neutrophil mobility, adherence, and chemotaxis. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C610 |
|
| Accepted_Therapeutic_Use_For |
Stage III Colon Cancer
|
|
| CAS_Registry |
16595-80-5
|
|
| Chemical_Formula |
C11H12N2S.HCl
|
|
| code |
C610
|
|
| Contributing_Source |
CTRP FDA
|
|
| definition |
The hydrochloride salt of the synthetic imidazothiazole derivative levamisole with anthelminthic and immunomodulating activities. In immunosuppressed states, levamisole may restore immune function by: 1) stimulating antibody formation, 2) stimulating T-cell activation and proliferation, 3) potentiating monocyte and macrophage phagocytosis and chemotaxis and 4) increasing neutrophil mobility, adherence, and chemotaxis.
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|
| Display_Name |
Levamisole Hydrochloride
|
|
| FDA_UNII_Code |
DL9055K809
|
|
| Has_Free_Acid_Or_Base_Form | ||
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C176424 |
|
| label |
Levamisole Hydrochloride
|
|
| Legacy Concept Name |
Levamisole
|
|
| NCI_Drug_Dictionary_ID |
39058
|
|
| NSC Number |
177023
|
|
| PDQ_Closed_Trial_Search_ID |
39058
|
|
| PDQ_Open_Trial_Search_ID |
39058
|
|
| Preferred_Name |
Levamisole Hydrochloride
|
|
| prefixIRI |
NCIT:C610
|
|
| prefLabel |
Levamisole Hydrochloride
|
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance
|
|
| UMLS_CUI |
C0733383
|
|
| subClassOf |
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