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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Basiliximab | |
| Synonyms |
|
|
| Definitions |
A recombinant, chimeric, human-murine monoclonal antibody directed against the alpha subunit of the interleukin-2 receptor (IL-2R alpha) with immunosuppressant activity. Basiliximab selectively binds to and blocks IL-2R alpha, expressed on the surface of activated T-lymphocytes, thereby preventing interleukin-2 binding and inhibiting the interleukin-2-mediated activation of lymphocytes. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C52186 |
|
| CAS_Registry |
179045-86-4
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|
| code |
C52186
|
|
| Contributing_Source |
CTRP FDA
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|
| definition |
A recombinant, chimeric, human-murine monoclonal antibody directed against the alpha subunit of the interleukin-2 receptor (IL-2R alpha) with immunosuppressant activity. Basiliximab selectively binds to and blocks IL-2R alpha, expressed on the surface of activated T-lymphocytes, thereby preventing interleukin-2 binding and inhibiting the interleukin-2-mediated activation of lymphocytes.
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|
| Display_Name |
Basiliximab
|
|
| FDA_UNII_Code |
9927MT646M
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|
| Has_Target | ||
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C176424 |
|
| label |
Basiliximab
|
|
| Legacy Concept Name |
Basiliximab
|
|
| NCI_Drug_Dictionary_ID |
459956
|
|
| PDQ_Closed_Trial_Search_ID |
459956
|
|
| PDQ_Open_Trial_Search_ID |
459956
|
|
| Preferred_Name |
Basiliximab
|
|
| prefixIRI |
NCIT:C52186
|
|
| prefLabel |
Basiliximab
|
|
| Semantic_Type |
Pharmacologic Substance
|
|
| UMLS_CUI |
C0676831
|
|
| subClassOf |
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