loading...| Preferred Name | Fluoxymesterone | |
| Synonyms |
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|
| Definitions |
A halogenated derivative of 17-alpha-methyltestosterone. Similar to testosterone, fluoxymesterone binds to and activates specific nuclear receptors, resulting in an increase in protein anabolism, a decrease in amino acid catabolism, and retention of nitrogen, potassium, and phosphorus. This agent also may competitively inhibit prolactin receptors and estrogen receptors, thereby inhibiting the growth of hormone-dependent tumor lines. Fluoxymesterone is approximately five times more potent than methyltestosterone. (NCI04) |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C507 |
|
| CAS_Registry |
76-43-7 |
|
| CHEBI_ID |
CHEBI:5120 |
|
| Chemical_Formula |
C20H29FO3 |
|
| code |
C507 |
|
| Contributing_Source |
FDA |
|
| definition |
A halogenated derivative of 17-alpha-methyltestosterone. Similar to testosterone, fluoxymesterone binds to and activates specific nuclear receptors, resulting in an increase in protein anabolism, a decrease in amino acid catabolism, and retention of nitrogen, potassium, and phosphorus. This agent also may competitively inhibit prolactin receptors and estrogen receptors, thereby inhibiting the growth of hormone-dependent tumor lines. Fluoxymesterone is approximately five times more potent than methyltestosterone. (NCI04) |
|
| FDA_UNII_Code |
9JU12S4YFY |
|
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C176424 http://purl.obolibrary.org/obo/NCIT_C128784 |
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| Is_Value_For_GDC_Property | ||
| label |
Fluoxymesterone |
|
| Legacy Concept Name |
Fluoxymesterone |
|
| Maps_To |
Fluoxymesterone |
|
| NCI_Drug_Dictionary_ID |
494707 |
|
| NSC Number |
12165 |
|
| PDQ_Closed_Trial_Search_ID |
494707 |
|
| PDQ_Open_Trial_Search_ID |
494707 |
|
| Preferred_Name |
Fluoxymesterone |
|
| prefixIRI |
NCIT:C507 |
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| prefLabel |
Fluoxymesterone |
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| Semantic_Type |
Organic Chemical Pharmacologic Substance |
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| UMLS_CUI |
C0016366 |
|
| subClassOf |