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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Iloprost | |
| Synonyms |
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| Definitions |
A prostacyclin analogue with potential chemopreventive activity. Iloprost binds to the prostacyclin receptor in various target cells, thereby causing vasodilation, inhibition of platelet aggregation, and decreased tumor cell adhesion to endothelium among other effects. Prostacyclin is a naturally occurring eicosanoid with anti-inflammatory, antineoplastic, and anti-metastatic properties. (NCI05) |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C48397 |
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| ALT_DEFINITION |
A substance that is being studied in the prevention of lung cancer. It belongs to the family of drugs called prostaglandin analogs.
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| CAS_Registry |
78919-13-8
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| CHEBI_ID |
CHEBI:63916
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| Chemical_Formula |
C22H32O4
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|
| code |
C48397
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| Contributing_Source |
FDA
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|
| definition |
A prostacyclin analogue with potential chemopreventive activity. Iloprost binds to the prostacyclin receptor in various target cells, thereby causing vasodilation, inhibition of platelet aggregation, and decreased tumor cell adhesion to endothelium among other effects. Prostacyclin is a naturally occurring eicosanoid with anti-inflammatory, antineoplastic, and anti-metastatic properties. (NCI05)
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| FDA_UNII_Code |
JED5K35YGL
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| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C173383 http://purl.obolibrary.org/obo/NCIT_C173381 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C176424 http://purl.obolibrary.org/obo/NCIT_C128784 |
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| Is_Value_For_GDC_Property | ||
| label |
Iloprost
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|
| Legacy Concept Name |
Iloprost
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|
| Maps_To |
Iloprost
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| NCI_Drug_Dictionary_ID |
365679
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| PDQ_Closed_Trial_Search_ID |
365679
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|
| PDQ_Open_Trial_Search_ID |
365679
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| Preferred_Name |
Iloprost
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| prefixIRI |
NCIT:C48397
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| prefLabel |
Iloprost
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| Semantic_Type |
Pharmacologic Substance
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| UMLS_CUI |
C0079594
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| subClassOf |
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