Preferred Name

Terbinafine
Synonyms
Definitions

A synthetic allylamine derivative with antifungal activity. Terbinafine exerts its effect through inhibition of squalene epoxidase, thereby blocking the biosynthesis of ergosterol, an important component of fungal cell membranes. As a result, this agent disrupts fungal cell membrane synthesis and inhibits fungal growth.

ID

http://purl.obolibrary.org/obo/NCIT_C48019

CAS_Registry

91161-71-6

Chemical_Formula

C21H25N

code

C48019

Contributing_Source

FDA

definition

A synthetic allylamine derivative with antifungal activity. Terbinafine exerts its effect through inhibition of squalene epoxidase, thereby blocking the biosynthesis of ergosterol, an important component of fungal cell membranes. As a result, this agent disrupts fungal cell membrane synthesis and inhibits fungal growth.

FDA_UNII_Code

G7RIW8S0XP

Has_Salt_Form

http://purl.obolibrary.org/obo/NCIT_C29492

in_subset

http://purl.obolibrary.org/obo/NCIT_C63923

label

Terbinafine

Legacy Concept Name

Terbinafine

Preferred_Name

Terbinafine

prefixIRI

NCIT:C48019

prefLabel

Terbinafine

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0076110

subClassOf

http://purl.obolibrary.org/obo/NCIT_C514

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Delete Mapping To Ontology Source
http://sbmi.uth.tmc.edu/ontology/ochv#14916 OCHV LOOM
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Terbinafine SEPON LOOM
http://www.drugbank.ca/drugs/DB00857 FTC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000021605 NDFRT LOOM
http://purl.bioontology.org/ontology/RXNORM/37801 RXNORM LOOM
http://stirdf.jst.go.jp/id/200907095366807234 IOBC LOOM
http://purl.bioontology.org/ontology/LNC/LP14848-3 LOINC LOOM
http://purl.obolibrary.org/obo/dinto_DB00857 DINTO LOOM
http://purl.bioontology.org/ontology/VANDF/4023600 VANDF LOOM
http://www.co-ode.org/ontologies/galen#Terbinafine GALEN LOOM
http://purl.obolibrary.org/obo/ARO_3007507 ARO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C041359 RH-MESH LOOM
http://purl.obolibrary.org/obo/CHEBI_9448 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_9448 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_9448 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_9448 HOIP LOOM
http://purl.obolibrary.org/obo/CHEBI_9448 COVID-19 LOOM
http://purl.obolibrary.org/obo/CHEBI_9448 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_9448 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_9448 TXPO LOOM
http://purl.obolibrary.org/obo/CHEBI_9448 UPHENO LOOM
http://purl.obolibrary.org/obo/CHEBI_9448 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_9448 PHIPO LOOM
http://purl.obolibrary.org/obo/CHEBI_9448 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_9448 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_9448 OBA LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C48019 NCIT LOOM
http://purl.jp/bio/4/id/200906017874991755 IOBC LOOM
http://purl.bioontology.org/ontology/ATC/D01BA02 ATC LOOM
http://purl.bioontology.org/ontology/LNC/MTHU002062 LOINC LOOM
http://purl.bioontology.org/ontology/RCD/x03eY RCD LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0076110 OCHV LOOM
https://go.drugbank.com/drugs/DB00857 MDM LOOM
http://www.phoc.org.cn/pmo/class/PMO_00025785 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/373450007 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/ATC/D01AE15 ATC LOOM
http://purl.bioontology.org/ontology/MESH/D000077291 MESH LOOM