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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Fentanyl Citrate | |
| Synonyms |
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| Definitions |
The citrate salt of fentanyl, a synthetic opioid related to the phenylpiperidines with analgesic and anesthetic properties. Fentanyl exerts its analgesic effect by selectively binding to the mu-opioid receptor in the central nervous system (CNS), thereby mimicking the effects of endogenous opiates. Additional pharmacological effects of fentanyl include anxiolysis, euphoria, feelings of relaxation, respiratory depression, constipation, miosis, and cough suppression. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C47994 |
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| Accepted_Therapeutic_Use_For |
breakthrough pain in cancer patients.
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| ALT_DEFINITION |
A drug used to treat severe cancer pain in that occurs even though the patient is already taking opioids. It is also used during anesthesia for surgery. Fentanyl citrate binds to opioid receptors in the central nervous system. It is a type of analgesic agent and a type of opioid.
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| CAS_Registry |
990-73-8
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| CHEBI_ID |
CHEBI:31602
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| Chemical_Formula |
C22H28N2O.C6H8O7
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|
| code |
C47994
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| Contributing_Source |
CPTAC CTRP FDA
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|
| definition |
The citrate salt of fentanyl, a synthetic opioid related to the phenylpiperidines with analgesic and anesthetic properties. Fentanyl exerts its analgesic effect by selectively binding to the mu-opioid receptor in the central nervous system (CNS), thereby mimicking the effects of endogenous opiates. Additional pharmacological effects of fentanyl include anxiolysis, euphoria, feelings of relaxation, respiratory depression, constipation, miosis, and cough suppression.
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| Display_Name |
Fentanyl Citrate
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| FDA_UNII_Code |
MUN5LYG46H
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| Has_Free_Acid_Or_Base_Form | ||
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C176424 http://purl.obolibrary.org/obo/NCIT_C156952 http://purl.obolibrary.org/obo/NCIT_C156953 http://purl.obolibrary.org/obo/NCIT_C116977 |
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| label |
Fentanyl Citrate
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|
| Legacy Concept Name |
Fentanyl_Citrate
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| NCI_Drug_Dictionary_ID |
39241
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| PDQ_Closed_Trial_Search_ID |
39241
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| PDQ_Open_Trial_Search_ID |
39241
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| Preferred_Name |
Fentanyl Citrate
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| prefixIRI |
NCIT:C47994
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|
| prefLabel |
Fentanyl Citrate
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| Semantic_Type |
Pharmacologic Substance
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| UMLS_CUI |
C0546864
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| subClassOf |
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