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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Zanamivir | |
| Synonyms |
|
|
| Definitions |
A sialic acid-analogue neuraminidase inhibitor with antiviral activity. Administered into the respiratory tract by aerosol inhalation, zanamivir selectively binds to and inhibits influenza A and B virus neuraminidase-mediated cleavage of sialic acid residues in host cell membrane-bound glycoprotein receptors for influenza viruses, preventing the release of progeny viruses from host cell surfaces and, so, further viral replication. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C47786 |
|
| ALT_DEFINITION |
A drug used to prevent and to treat influenza virus infections. It blocks the release of the virus from infected cells. It is a type of antiviral agent.
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|
| CAS_Registry |
139110-80-8
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|
| CHEBI_ID |
CHEBI:50663
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|
| Chemical_Formula |
C12H20N4O7
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|
| code |
C47786
|
|
| Contributing_Source |
CTRP FDA
|
|
| definition |
A sialic acid-analogue neuraminidase inhibitor with antiviral activity. Administered into the respiratory tract by aerosol inhalation, zanamivir selectively binds to and inhibits influenza A and B virus neuraminidase-mediated cleavage of sialic acid residues in host cell membrane-bound glycoprotein receptors for influenza viruses, preventing the release of progeny viruses from host cell surfaces and, so, further viral replication.
|
|
| Display_Name |
Zanamivir
|
|
| FDA_UNII_Code |
L6O3XI777I
|
|
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C176424 |
|
| label |
Zanamivir
|
|
| Legacy Concept Name |
Zanamivir
|
|
| NCI_Drug_Dictionary_ID |
636195
|
|
| PDQ_Closed_Trial_Search_ID |
636195
|
|
| PDQ_Open_Trial_Search_ID |
636195
|
|
| Preferred_Name |
Zanamivir
|
|
| prefixIRI |
NCIT:C47786
|
|
| prefLabel |
Zanamivir
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|
| Semantic_Type |
Pharmacologic Substance
|
|
| UMLS_CUI |
C0216660
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|
| subClassOf |
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