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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Repaglinide | |
| Synonyms |
|
|
| Definitions |
A nonsulfonylurea insulin secretagogue belonging to the melgitinide class with hypoglycemic activity. Repaglinide is rapidly absorbed and has a rapid onset and short duration of action. This agent is metabolized in the liver by CYP2C8 and CYP3A4 and its metabolites are excreted in the bile. Repaglinide has a half-life of one hour. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C47703 |
|
| CAS_Registry |
135062-02-1
|
|
| Chemical_Formula |
C27H36N2O4
|
|
| code |
C47703
|
|
| Contributing_Source |
CTRP FDA
|
|
| definition |
A nonsulfonylurea insulin secretagogue belonging to the melgitinide class with hypoglycemic activity. Repaglinide is rapidly absorbed and has a rapid onset and short duration of action. This agent is metabolized in the liver by CYP2C8 and CYP3A4 and its metabolites are excreted in the bile. Repaglinide has a half-life of one hour.
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|
| Display_Name |
Repaglinide
|
|
| FDA_UNII_Code |
668Z8C33LU
|
|
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C176424 |
|
| label |
Repaglinide
|
|
| Legacy Concept Name |
Repaglinide
|
|
| NCI_Drug_Dictionary_ID |
775334
|
|
| PDQ_Closed_Trial_Search_ID |
775334
|
|
| PDQ_Open_Trial_Search_ID |
775334
|
|
| Preferred_Name |
Repaglinide
|
|
| prefixIRI |
NCIT:C47703
|
|
| prefLabel |
Repaglinide
|
|
| Semantic_Type |
Pharmacologic Substance
|
|
| UMLS_CUI |
C0246689
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|
| subClassOf |
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