loading...| Preferred Name | Pirbuterol Acetate | |
| Synonyms |
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| Definitions |
The acetate salt form of pirbuterol, a synthetic catecholamine and a pyridine derivative with sympathomimetic and bronchodilatory effects. Pirbuterol acetate selectively stimulates beta-2 adrenergic receptors, resulting in initiation of intracellular adenylate cyclase activity leading to increased levels of cAMP. As a result muscle relaxation (broncho- and vasodilation) occurs via cAMP-dependent signal transduction. In addition, elevated levels of cAMP inhibit release of inflammatory mediators from mast cells. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C47675 |
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| CAS_Registry |
65652-44-0 |
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| Chemical_Formula |
C12H20N2O3.C2H4O2 |
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| code |
C47675 |
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| Contributing_Source |
FDA |
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| definition |
The acetate salt form of pirbuterol, a synthetic catecholamine and a pyridine derivative with sympathomimetic and bronchodilatory effects. Pirbuterol acetate selectively stimulates beta-2 adrenergic receptors, resulting in initiation of intracellular adenylate cyclase activity leading to increased levels of cAMP. As a result muscle relaxation (broncho- and vasodilation) occurs via cAMP-dependent signal transduction. In addition, elevated levels of cAMP inhibit release of inflammatory mediators from mast cells. |
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| FDA_UNII_Code |
1EH73XKR9N |
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| Has_Free_Acid_Or_Base_Form | ||
| in_subset | ||
| label |
Pirbuterol Acetate |
|
| Legacy Concept Name |
Pirbuterol_Acetate |
|
| Preferred_Name |
Pirbuterol Acetate |
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| prefixIRI |
NCIT:C47675 |
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| prefLabel |
Pirbuterol Acetate |
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| Semantic_Type |
Pharmacologic Substance |
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| UMLS_CUI |
C0724666 |
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| subClassOf |