Preferred Name

Pemirolast Potassium

Synonyms
Definitions

The potassium salt form of pemirolast, a pyrimidinone derivative with antiallergic property. Pemirolast potassium exerts its action by blocking the antigen-mediated calcium ion influx into mast cells. This prevents mast cell degranulation, resulting in mast cell stabilization and inhibition of the release of inflammatory mediators, histamine and leukotrienes, which are involved in the allergic process. Pemirolast potassium also prevents inflammatory mediator release from eosinophils.

ID

http://purl.obolibrary.org/obo/NCIT_C47654

CAS_Registry

100299-08-9

Chemical_Formula

C10H7N6O.K

code

C47654

Contributing_Source

FDA

definition

The potassium salt form of pemirolast, a pyrimidinone derivative with antiallergic property. Pemirolast potassium exerts its action by blocking the antigen-mediated calcium ion influx into mast cells. This prevents mast cell degranulation, resulting in mast cell stabilization and inhibition of the release of inflammatory mediators, histamine and leukotrienes, which are involved in the allergic process. Pemirolast potassium also prevents inflammatory mediator release from eosinophils.

FDA_UNII_Code

497A17OUUE

Has_Free_Acid_Or_Base_Form

http://purl.obolibrary.org/obo/NCIT_C66334

in_subset

http://purl.obolibrary.org/obo/NCIT_C63923

label

Pemirolast Potassium

Legacy Concept Name

Pemirolast_Potassium

Preferred_Name

Pemirolast Potassium

prefixIRI

NCIT:C47654

prefLabel

Pemirolast Potassium

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0872971

subClassOf

http://purl.obolibrary.org/obo/NCIT_C29714

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