loading...| Preferred Name |
Natamycin |
|
| Synonyms |
|
|
| Definitions |
A polyene amphoteric macrolide antibiotic with antifungal properties. Natamycin exerts its antifungal effects by binding to sterols in the fungal cell membrane thereby increasing membrane permeability. This leads to a leakage and loss of essential cellular constituents. Following ocular application, natamycin is retained in the conjunctival fornices and attains effective concentrations within the corneal stroma where it exerts its effect. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C47634 |
|
| CAS_Registry |
7681-93-8 |
|
| Chemical_Formula |
C33H47NO13 |
|
| code |
C47634 |
|
| Contributing_Source |
FDA |
|
| definition |
A polyene amphoteric macrolide antibiotic with antifungal properties. Natamycin exerts its antifungal effects by binding to sterols in the fungal cell membrane thereby increasing membrane permeability. This leads to a leakage and loss of essential cellular constituents. Following ocular application, natamycin is retained in the conjunctival fornices and attains effective concentrations within the corneal stroma where it exerts its effect. |
|
| FDA_UNII_Code |
8O0C852CPO |
|
| in_subset | ||
| label |
Natamycin |
|
| Legacy Concept Name |
Natamycin |
|
| Preferred_Name |
Natamycin |
|
| prefixIRI |
NCIT:C47634 |
|
| prefLabel |
Natamycin |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0027444 |
|
| subClassOf |