Preferred Name |
Mefenamic Acid |
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Synonyms |
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Definitions |
An anthranilic acid and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activities. Mefenamic acid inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis, by prostaglandin synthase, is responsible for the therapeutic effects of mefenamic acid. Mefenamic acid also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation. |
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ID |
http://purl.obolibrary.org/obo/NCIT_C47599 |
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CAS_Registry |
61-68-7 |
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Chemical_Formula |
C15H15NO2 |
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code |
C47599 |
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Contributing_Source |
FDA |
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definition |
An anthranilic acid and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activities. Mefenamic acid inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis, by prostaglandin synthase, is responsible for the therapeutic effects of mefenamic acid. Mefenamic acid also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation. |
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FDA_UNII_Code |
367589PJ2C |
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in_subset | ||
label |
Mefenamic Acid |
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Legacy Concept Name |
Mefenamic_Acid |
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NSC Number |
94437 |
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Preferred_Name |
Mefenamic Acid |
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prefixIRI |
NCIT:C47599 |
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prefLabel |
Mefenamic Acid |
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PubMedID_Primary_Reference |
2242038 |
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Semantic_Type |
Pharmacologic Substance |
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UMLS_CUI |
C0025152 |
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subClassOf |