loading...| Preferred Name | Lomefloxacin Hydrochloride | |
| Synonyms |
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|
| Definitions |
The hydrochloride salt form of lomefloxacin, a synthetic broad-spectrum fluoroquinolone with antibacterial activity. Lomefloxacin hydrochloride inhibits DNA gyrase, a type II topoisomerase involved in the induction or relaxation of supercoiling during DNA replication. This inhibition leads to a decrease in DNA synthesis during bacterial replication, resulting in cell growth inhibition and eventually cell lysis. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C47587 |
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| CAS_Registry |
98079-52-8 |
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| CHEBI_ID |
CHEBI:6518 |
|
| Chemical_Formula |
C17H19F2N3O3.HCl |
|
| code |
C47587 |
|
| Contributing_Source |
FDA |
|
| definition |
The hydrochloride salt form of lomefloxacin, a synthetic broad-spectrum fluoroquinolone with antibacterial activity. Lomefloxacin hydrochloride inhibits DNA gyrase, a type II topoisomerase involved in the induction or relaxation of supercoiling during DNA replication. This inhibition leads to a decrease in DNA synthesis during bacterial replication, resulting in cell growth inhibition and eventually cell lysis. |
|
| FDA_UNII_Code |
9VC7S3ZXXB |
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| Has_Free_Acid_Or_Base_Form | ||
| in_subset | ||
| label |
Lomefloxacin Hydrochloride |
|
| Legacy Concept Name |
Lomefloxacin_Hydrochloride |
|
| Preferred_Name |
Lomefloxacin Hydrochloride |
|
| prefixIRI |
NCIT:C47587 |
|
| prefLabel |
Lomefloxacin Hydrochloride |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0770927 |
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| subClassOf |