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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Ketotifen Fumarate | |
| Synonyms |
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| Definitions |
The fumarate salt of ketotifen, a cycloheptathiophene derivative with anti-allergic activity. Ketotifen selectively blocks histamine (H1) receptors and prevents the typical symptoms caused by histamine release. This agent also interferes with the release of inflammatory mediators from mast cells involved in hypersensitivity reactions, thereby decreasing chemotaxis and activation of eosinophils. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C47579 |
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| CAS_Registry |
34580-14-8
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| Chemical_Formula |
C19H19NOS.C4H4O4
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| code |
C47579
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| Contributing_Source |
FDA
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| definition |
The fumarate salt of ketotifen, a cycloheptathiophene derivative with anti-allergic activity. Ketotifen selectively blocks histamine (H1) receptors and prevents the typical symptoms caused by histamine release. This agent also interferes with the release of inflammatory mediators from mast cells involved in hypersensitivity reactions, thereby decreasing chemotaxis and activation of eosinophils.
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| FDA_UNII_Code |
HBD503WORO
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| Has_Free_Acid_Or_Base_Form | ||
| in_subset | ||
| label |
Ketotifen Fumarate
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| Legacy Concept Name |
Ketotifen_Fumarate
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| NCI_Drug_Dictionary_ID |
804026
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| PDQ_Closed_Trial_Search_ID |
804026
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| PDQ_Open_Trial_Search_ID |
804026
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| Preferred_Name |
Ketotifen Fumarate
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| prefixIRI |
NCIT:C47579
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| prefLabel |
Ketotifen Fumarate
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| Semantic_Type |
Pharmacologic Substance
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| UMLS_CUI |
C0043443
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| subClassOf |
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