Link to this page
Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
Jump to:
| Preferred Name | Guanfacine Hydrochloride | |
| Synonyms |
|
|
| Definitions |
The hydrochloride salt form of guanfacine, a centrally acting alpha-2 adrenergic agonist with antihypertensive activity. Alpha-2 receptor stimulation by guanfacine hydrochloride results in a decreased sympathetic outflow from the vasomotor center to the heart, kidneys, and peripheral vasculature. This leads to a decrease in heart rate and peripheral vascular resistance. (NCI05) |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C47550 |
|
| CAS_Registry |
29110-48-3
|
|
| Chemical_Formula |
C9H9Cl2N3O.HCl
|
|
| code |
C47550
|
|
| Contributing_Source |
FDA
|
|
| definition |
The hydrochloride salt form of guanfacine, a centrally acting alpha-2 adrenergic agonist with antihypertensive activity. Alpha-2 receptor stimulation by guanfacine hydrochloride results in a decreased sympathetic outflow from the vasomotor center to the heart, kidneys, and peripheral vasculature. This leads to a decrease in heart rate and peripheral vascular resistance. (NCI05)
|
|
| FDA_UNII_Code |
PML56A160O
|
|
| Has_Free_Acid_Or_Base_Form | ||
| in_subset | ||
| label |
Guanfacine Hydrochloride
|
|
| Legacy Concept Name |
Guanfacine_Hydrochloride
|
|
| Preferred_Name |
Guanfacine Hydrochloride
|
|
| prefixIRI |
NCIT:C47550
|
|
| prefLabel |
Guanfacine Hydrochloride
|
|
| Semantic_Type |
Pharmacologic Substance
|
|
| UMLS_CUI |
C0700472
|
|
| subClassOf |
Add comment
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |
Create mapping