loading...| Preferred Name | Fenoldopam Mesylate | |
| Synonyms |
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| Definitions |
The mesylate salt form of fenoldopam, a benzazepine derivative with rapid-acting vasodilator activity. Fenoldopam mesylate is a racemic mixture of S- and R- isomers; the latter is responsible for the biological activity and has a significantly higher affinity for dopamine D1-like receptors (D1 and D5) as well as moderate affinity to alpha-2 adrenergic receptors. This agent selectively activates the dopamine D1-like receptor, thereby causing vasodilatation and increasing renal perfusion. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C47531 |
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| CAS_Registry |
67227-57-0 |
|
| Chemical_Formula |
C16H16ClNO3.CH4O3S |
|
| code |
C47531 |
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| Contributing_Source |
FDA |
|
| definition |
The mesylate salt form of fenoldopam, a benzazepine derivative with rapid-acting vasodilator activity. Fenoldopam mesylate is a racemic mixture of S- and R- isomers; the latter is responsible for the biological activity and has a significantly higher affinity for dopamine D1-like receptors (D1 and D5) as well as moderate affinity to alpha-2 adrenergic receptors. This agent selectively activates the dopamine D1-like receptor, thereby causing vasodilatation and increasing renal perfusion. |
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| FDA_UNII_Code |
HA3R0MY016 |
|
| Has_Free_Acid_Or_Base_Form | ||
| in_subset | ||
| label |
Fenoldopam Mesylate |
|
| Legacy Concept Name |
Fenoldopam_Mesylate |
|
| Preferred_Name |
Fenoldopam Mesylate |
|
| prefixIRI |
NCIT:C47531 |
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| prefLabel |
Fenoldopam Mesylate |
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| Semantic_Type |
Pharmacologic Substance |
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| UMLS_CUI |
C0700481 |
|
| subClassOf |