Preferred Name

Dyphylline
Synonyms
Definitions

A xanthine derivative. Dyphilline exerts bronchodilator effects and to a lesser extent vasodilator and diuretic properties. Dyphilline probably acts as a competitive inhibitor of phosphodiesterase which leads to an increase in intracellular cAMP. This results in relaxation of bronchial smooth muscle and other smooth muscles. Dyphylline may also antagonize adenosine receptors. Dyphylline is used in the treatment of acute bronchial asthma, chronic bronchitis and emphysema.

ID

http://purl.obolibrary.org/obo/NCIT_C47504

CAS_Registry

479-18-5

CHEBI_ID

CHEBI:4728

Chemical_Formula

C10H14N4O4

code

C47504

Contributing_Source

FDA

definition

A xanthine derivative. Dyphilline exerts bronchodilator effects and to a lesser extent vasodilator and diuretic properties. Dyphilline probably acts as a competitive inhibitor of phosphodiesterase which leads to an increase in intracellular cAMP. This results in relaxation of bronchial smooth muscle and other smooth muscles. Dyphylline may also antagonize adenosine receptors. Dyphylline is used in the treatment of acute bronchial asthma, chronic bronchitis and emphysema.

FDA_UNII_Code

263T0E9RR9

in_subset

http://purl.obolibrary.org/obo/NCIT_C63923

label

Dyphylline

Legacy Concept Name

Dyphylline

NSC Number

14305

Preferred_Name

Dyphylline

prefixIRI

NCIT:C47504

prefLabel

Dyphylline

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0013360

subClassOf

http://purl.obolibrary.org/obo/NCIT_C319

http://purl.obolibrary.org/obo/NCIT_C744

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