loading...| Preferred Name |
Dexchlorpheniramine Maleate |
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| Synonyms |
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| Definitions |
The maleate salt form of dexchlorpheniramine, an alkylamine, and first-generation histamine antagonist with anti-allergic activity. Dexchlorpheniramine maleate competitively blocks H1 receptors, thereby preventing the actions of histamine on bronchial smooth muscle, capillaries and gastrointestinal (GI) smooth muscle. This prevents histamine-induced bronchoconstriction, vasodilation, increased capillary permeability, and GI smooth muscle spasms. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C47478 |
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| CAS_Registry |
2438-32-6 |
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| Chemical_Formula |
C16H19ClN2.C4H4O4 |
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| code |
C47478 |
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| Contributing_Source |
FDA |
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| definition |
The maleate salt form of dexchlorpheniramine, an alkylamine, and first-generation histamine antagonist with anti-allergic activity. Dexchlorpheniramine maleate competitively blocks H1 receptors, thereby preventing the actions of histamine on bronchial smooth muscle, capillaries and gastrointestinal (GI) smooth muscle. This prevents histamine-induced bronchoconstriction, vasodilation, increased capillary permeability, and GI smooth muscle spasms. |
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| FDA_UNII_Code |
B10YD955QW |
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| Has_Free_Acid_Or_Base_Form | ||
| in_subset | ||
| label |
Dexchlorpheniramine Maleate |
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| Legacy Concept Name |
Dexchlorpheniramine_Maleate |
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| Preferred_Name |
Dexchlorpheniramine Maleate |
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| prefixIRI |
NCIT:C47478 |
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| prefLabel |
Dexchlorpheniramine Maleate |
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| Semantic_Type |
Pharmacologic Substance |
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| UMLS_CUI |
C0137440 |
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| subClassOf |