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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Clofazimine | |
| Synonyms |
|
|
| Definitions |
A phenazine dye with anti-mycobacterial and anti-inflammatory activities. The exact mechanism through which clofazimine exerts its effect is unknown. However, it binds preferentially to mycobacterial DNA, thereby inhibiting DNA replication and cell growth. Clofazimine has a slow bactericidal effect on Mycobacterium leprae and is active against various other Mycobacteria. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C47456 |
|
| CAS_Registry |
2030-63-9
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| CHEBI_ID |
CHEBI:3749
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|
| code |
C47456
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| Contributing_Source |
FDA
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|
| definition |
A phenazine dye with anti-mycobacterial and anti-inflammatory activities. The exact mechanism through which clofazimine exerts its effect is unknown. However, it binds preferentially to mycobacterial DNA, thereby inhibiting DNA replication and cell growth. Clofazimine has a slow bactericidal effect on Mycobacterium leprae and is active against various other Mycobacteria.
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|
| FDA_UNII_Code |
D959AE5USF
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|
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 |
|
| label |
Clofazimine
|
|
| Legacy Concept Name |
Clofazimine
|
|
| NSC Number |
141046
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|
| Preferred_Name |
Clofazimine
|
|
| prefixIRI |
NCIT:C47456
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|
| prefLabel |
Clofazimine
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|
| Semantic_Type |
Pharmacologic Substance
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|
| UMLS_CUI |
C0008996
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|
| subClassOf |
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