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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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Preferred Name | Brompheniramine Maleate | |
Synonyms |
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Definitions |
The maleate salt form of brompheniramine, an alkylamine derivative and a histamine antagonist with anticholinergic and sedative properties. Brompheniramine maleate competes with histamine for the H1 receptor. This diminishes the actions of histamine on effector cells and decreases the histamine-mediated symptoms of allergic reaction such as bronchoconstriction, vasodilation, increased capillary permeability and spasmodic contractions of gastrointestinal smooth muscle. |
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ID |
http://purl.obolibrary.org/obo/NCIT_C47422 |
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CAS_Registry |
980-71-2
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CHEBI_ID |
CHEBI:3184
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Chemical_Formula |
C16H19BrN2.C4H4O4
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code |
C47422
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Contributing_Source |
FDA
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definition |
The maleate salt form of brompheniramine, an alkylamine derivative and a histamine antagonist with anticholinergic and sedative properties. Brompheniramine maleate competes with histamine for the H1 receptor. This diminishes the actions of histamine on effector cells and decreases the histamine-mediated symptoms of allergic reaction such as bronchoconstriction, vasodilation, increased capillary permeability and spasmodic contractions of gastrointestinal smooth muscle.
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FDA_UNII_Code |
IXA7C9ZN03
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Has_Free_Acid_Or_Base_Form | ||
in_subset | ||
label |
Brompheniramine Maleate
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Legacy Concept Name |
Brompheniramine_Maleate
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Preferred_Name |
Brompheniramine Maleate
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prefixIRI |
NCIT:C47422
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prefLabel |
Brompheniramine Maleate
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Semantic_Type |
Pharmacologic Substance
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UMLS_CUI |
C0546853
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subClassOf |
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