Link to this page
Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
Jump to:
| Preferred Name | Azelastine Hydrochloride | |
| Synonyms |
|
|
| Definitions |
The hydrochloride salt form of azelastine, a phthalazinone derivative with antihistaminergic activity. Azelastine hydrochloride competes with histamine for the H1 receptor, thereby diminishing the actions of histamine on effector cells and decreasing the histamine-mediated symptoms of allergic reaction, such as bronchoconstriction, vasodilation, increased capillary permeability and spasmodic contractions of gastrointestinal smooth muscle. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C47408 |
|
| Accepted_Therapeutic_Use_For |
seasonal allergic rhinitis
|
|
| CAS_Registry |
79307-93-0
|
|
| CHEBI_ID |
CHEBI:2951
|
|
| Chemical_Formula |
C22H24ClN3O.HCl
|
|
| code |
C47408
|
|
| Contributing_Source |
FDA
|
|
| definition |
The hydrochloride salt form of azelastine, a phthalazinone derivative with antihistaminergic activity. Azelastine hydrochloride competes with histamine for the H1 receptor, thereby diminishing the actions of histamine on effector cells and decreasing the histamine-mediated symptoms of allergic reaction, such as bronchoconstriction, vasodilation, increased capillary permeability and spasmodic contractions of gastrointestinal smooth muscle.
|
|
| FDA_UNII_Code |
0L591QR10I
|
|
| Has_Free_Acid_Or_Base_Form | ||
| in_subset | ||
| label |
Azelastine Hydrochloride
|
|
| Legacy Concept Name |
Azelastine_Hydrochloride
|
|
| Preferred_Name |
Azelastine Hydrochloride
|
|
| prefixIRI |
NCIT:C47408
|
|
| prefLabel |
Azelastine Hydrochloride
|
|
| Semantic_Type |
Pharmacologic Substance
|
|
| UMLS_CUI |
C0771004
|
|
| subClassOf |
Add comment
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |
Create mapping