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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Dextromethorphan Hydrobromide | |
| Synonyms |
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| Definitions |
The hydrobromide salt form of dextromethorphan, a synthetic, methylated dextrorotary analogue of levorphanol, a substance related to codeine and a non-opioid derivate of morphine. Dextromethorphan exhibits antitussive activity and is devoid of analgesic or addictive property. This agent crosses the blood-brain-barrier and activates sigma opioid receptors on the cough center in the central nervous system, thereby suppressing the cough reflex. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C423 |
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| CAS_Registry |
6700-34-1
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| Chemical_Formula |
C18H25NO.BrH.H2O
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| code |
C423
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| Contributing_Source |
CTRP FDA
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| definition |
The hydrobromide salt form of dextromethorphan, a synthetic, methylated dextrorotary analogue of levorphanol, a substance related to codeine and a non-opioid derivate of morphine. Dextromethorphan exhibits antitussive activity and is devoid of analgesic or addictive property. This agent crosses the blood-brain-barrier and activates sigma opioid receptors on the cough center in the central nervous system, thereby suppressing the cough reflex.
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| Display_Name |
Dextromethorphan Hydrobromide
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| FDA_UNII_Code |
9D2RTI9KYH
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| Has_Free_Acid_Or_Base_Form | ||
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C176424 |
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| label |
Dextromethorphan Hydrobromide
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| Legacy Concept Name |
Dextromethorphan
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| NCI_Drug_Dictionary_ID |
42490
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| NSC Number |
34521
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| PDQ_Closed_Trial_Search_ID |
42490
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| PDQ_Open_Trial_Search_ID |
42490
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| Preferred_Name |
Dextromethorphan Hydrobromide
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| prefixIRI |
NCIT:C423
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| prefLabel |
Dextromethorphan Hydrobromide
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| Semantic_Type |
Organic Chemical Pharmacologic Substance
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| UMLS_CUI |
C0350422
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| subClassOf |
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