loading...| Preferred Name |
Troponin T |
|
| Synonyms |
|
|
| Definitions |
Troponin I, troponin T, and troponin C are the three closely associated subunits of the troponin complex of thin filaments in muscle. The complex serves as a calcium-sensitive switch that regulates muscle contraction. Troponin T binds tropomyosin to the troponin complex and inhibits F-actin-myosin interactions. The troponin T gene family comprises three isoforms: slow skeletal (TNNT1), cardiac (TNNT2) and fast skeletal (TNNT3). Because it is not normally found in blood, cardiac troponin-T in serum is a sensitive indicator of myocardial cell injury. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C38041 |
|
| code |
C38041 |
|
| definition |
Troponin I, troponin T, and troponin C are the three closely associated subunits of the troponin complex of thin filaments in muscle. The complex serves as a calcium-sensitive switch that regulates muscle contraction. Troponin T binds tropomyosin to the troponin complex and inhibits F-actin-myosin interactions. The troponin T gene family comprises three isoforms: slow skeletal (TNNT1), cardiac (TNNT2) and fast skeletal (TNNT3). Because it is not normally found in blood, cardiac troponin-T in serum is a sensitive indicator of myocardial cell injury. |
|
| label |
Troponin T |
|
| Legacy Concept Name |
Troponin_T |
|
| Preferred_Name |
Troponin T |
|
| prefixIRI |
NCIT:C38041 |
|
| prefLabel |
Troponin T |
|
| Semantic_Type |
Amino Acid, Peptide, or Protein |
|
| UMLS_CUI |
C0077404 |
|
| subClassOf |