loading...| Preferred Name |
Clomiphene Citrate |
|
| Synonyms |
|
|
| Definitions |
The citrate salt form of clomiphene, a triphenylethylene nonsteroidal ovulatory stimulant evaluated for antineoplastic activity against breast cancer. Clomiphene has both estrogenic and anti-estrogenic activities that compete with estrogen for binding at estrogen receptor sites in target tissues. This agent causes the release of the pituitary gonadotropins follicle stimulating hormone (FSH) and luteinizing hormone (LH), leading to ovulation. (NCI04) |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C379 |
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| CAS_Registry |
50-41-9 |
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| CHEBI_ID |
CHEBI:3753 |
|
| code |
C379 |
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| Contributing_Source |
FDA |
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| definition |
The citrate salt form of clomiphene, a triphenylethylene nonsteroidal ovulatory stimulant evaluated for antineoplastic activity against breast cancer. Clomiphene has both estrogenic and anti-estrogenic activities that compete with estrogen for binding at estrogen receptor sites in target tissues. This agent causes the release of the pituitary gonadotropins follicle stimulating hormone (FSH) and luteinizing hormone (LH), leading to ovulation. (NCI04) |
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| FDA_UNII_Code |
1B8447E7YI |
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| Has_Free_Acid_Or_Base_Form | ||
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C176424 http://purl.obolibrary.org/obo/NCIT_C128784 |
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| Is_Value_For_GDC_Property | ||
| label |
Clomiphene Citrate |
|
| Legacy Concept Name |
Clomiphene |
|
| Maps_To |
Clomiphene Citrate |
|
| NCI_Drug_Dictionary_ID |
39542 |
|
| NSC Number |
35770 |
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| PDQ_Closed_Trial_Search_ID |
39542 |
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| PDQ_Open_Trial_Search_ID |
39542 |
|
| Preferred_Name |
Clomiphene Citrate |
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| prefixIRI |
NCIT:C379 |
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| prefLabel |
Clomiphene Citrate |
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| Semantic_Type |
Organic Chemical Pharmacologic Substance |
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| UMLS_CUI |
C0546859 |
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| subClassOf |