loading...| Preferred Name |
Paraneoplastic Syndrome |
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| Synonyms |
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| Definitions |
A classification for rare disorders of diverse organ systems (endocrine, neuromuscular, gastrointestinal, renal, dermatologic, rheumatologic, hematologic) that are affected by substances secreted by a distant neoplasm but not by the action of the neoplasm itself metastasizing to that organ or tissue. Less than 1 % of neoplasms are associated with these syndromes. An immune-mediated response to neoplasm-elaborated proteins may be the cause of these syndromes. Additionally, their manifestation may signal the presence of an occult neoplasm, potentially at an earlier stage of disease thereby leading to a better clinical outcome. Constitutional signs may include fever, night sweats, anorexia and cachexia. Clinical course is usually progressive. Prognosis is variable depending on the effective treatment of the underlying neoplasm. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C3311 |
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| ALT_DEFINITION |
A group of symptoms that may develop when substances released by some cancer cells disrupt the normal function of surrounding cells and tissue. |
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| code |
C3311 |
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| definition |
A classification for rare disorders of diverse organ systems (endocrine, neuromuscular, gastrointestinal, renal, dermatologic, rheumatologic, hematologic) that are affected by substances secreted by a distant neoplasm but not by the action of the neoplasm itself metastasizing to that organ or tissue. Less than 1 % of neoplasms are associated with these syndromes. An immune-mediated response to neoplasm-elaborated proteins may be the cause of these syndromes. Additionally, their manifestation may signal the presence of an occult neoplasm, potentially at an earlier stage of disease thereby leading to a better clinical outcome. Constitutional signs may include fever, night sweats, anorexia and cachexia. Clinical course is usually progressive. Prognosis is variable depending on the effective treatment of the underlying neoplasm. |
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| label |
Paraneoplastic Syndrome |
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| Legacy Concept Name |
Paraneoplastic_Syndrome |
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| Preferred_Name |
Paraneoplastic Syndrome |
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| prefixIRI |
NCIT:C3311 |
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| prefLabel |
Paraneoplastic Syndrome |
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| Semantic_Type |
Disease or Syndrome |
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| UMLS_CUI |
C0030472 |
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| subClassOf |