loading...| Preferred Name |
Type IV Hypersensitivity |
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| Synonyms |
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| Definitions |
Delayed hypersensitivity reaction (DTH) - type IV reaction, an inflammatory response that develops 24 to 72 hours after exposure to an antigen that the immune system recognizes as foreign. DTH is mediated by T cells rather than by antibodies. Th1 cells produce interferon gamma, interleukin (IL)-2, and tumor necrosis factor-beta and promote a cell-mediated immune response. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C3115 |
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| ALT_DEFINITION |
An inflammatory response that develops 24 to 72 hours after exposure to an antigen that the immune system recognizes as foreign. This type of immune response involves mainly T cells rather than antibodies (which are made by B cells). A hypersensitivity reaction triggered by sensitized T lymphocytes encountering antigens. These reactions usually develop 18 to 24 hours after exposure. |
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| code |
C3115 |
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| Contributing_Source |
CTRP MedDRA NICHD |
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| definition |
Delayed hypersensitivity reaction (DTH) - type IV reaction, an inflammatory response that develops 24 to 72 hours after exposure to an antigen that the immune system recognizes as foreign. DTH is mediated by T cells rather than by antibodies. Th1 cells produce interferon gamma, interleukin (IL)-2, and tumor necrosis factor-beta and promote a cell-mediated immune response. |
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| Display_Name |
Type IV Hypersensitivity |
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| in_subset |
http://purl.obolibrary.org/obo/NCIT_C90259 http://purl.obolibrary.org/obo/NCIT_C116977 |
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| label |
Type IV Hypersensitivity |
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| Legacy Concept Name |
Delayed-Type_Hypersensitivity |
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| Maps_To |
Type IV hypersensitivity reaction |
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| Preferred_Name |
Type IV Hypersensitivity |
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| prefixIRI |
NCIT:C3115 |
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| prefLabel |
Type IV Hypersensitivity |
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| Semantic_Type |
Disease or Syndrome |
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| UMLS_CUI |
C0020522 |
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| subClassOf |