loading...| Preferred Name |
Diphenhydramine Hydrochloride |
|
| Synonyms |
|
|
| Definitions |
The hydrochloride salt form of diphenhydramine, an ethanolamine and first-generation histamine antagonist with anti-allergic activity. Diphenhydramine hydrochloride competitively blocks H1receptors, thereby preventing the actions of histamine on bronchial smooth muscle, capillaries, and gastrointestinal (GI) smooth muscle. This prevents histamine-induced bronchoconstriction, vasodilation, increased capillary permeability, and GI smooth muscle spasms. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C300 |
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| CAS_Registry |
147-24-0 |
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| CHEBI_ID |
CHEBI:4637 |
|
| Chemical_Formula |
C17H21NO.HCl |
|
| code |
C300 |
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| Contributing_Source |
CTRP FDA |
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| definition |
The hydrochloride salt form of diphenhydramine, an ethanolamine and first-generation histamine antagonist with anti-allergic activity. Diphenhydramine hydrochloride competitively blocks H1receptors, thereby preventing the actions of histamine on bronchial smooth muscle, capillaries, and gastrointestinal (GI) smooth muscle. This prevents histamine-induced bronchoconstriction, vasodilation, increased capillary permeability, and GI smooth muscle spasms. |
|
| Display_Name |
Diphenhydramine Hydrochloride |
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| FDA_UNII_Code |
TC2D6JAD40 |
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| Has_Free_Acid_Or_Base_Form | ||
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C176424 |
|
| label |
Diphenhydramine Hydrochloride |
|
| Legacy Concept Name |
Diphenhydramine_Hydrochloride |
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| NCI_Drug_Dictionary_ID |
39163 |
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| NSC Number |
33299 |
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| PDQ_Closed_Trial_Search_ID |
39163 |
|
| PDQ_Open_Trial_Search_ID |
39163 |
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| Preferred_Name |
Diphenhydramine Hydrochloride |
|
| prefixIRI |
NCIT:C300 |
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| prefLabel |
Diphenhydramine Hydrochloride |
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| Semantic_Type |
Organic Chemical Pharmacologic Substance |
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| UMLS_CUI |
C0004963 |
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| subClassOf |