Preferred Name |
Beclomethasone Dipropionate |
|
Synonyms |
|
|
Definitions |
The dipropionate ester of a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, beclomethasone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. |
|
ID |
http://purl.obolibrary.org/obo/NCIT_C299 |
|
Accepted_Therapeutic_Use_For |
Asthma; GI graft vs. host disease, prevention; Nasal polyps; Rhinitis |
|
CAS_Registry |
5534-09-8 |
|
CHEBI_ID |
CHEBI:3002 |
|
Chemical_Formula |
C28H37ClO7 |
|
code |
C299 |
|
Contributing_Source |
CTRP FDA HL7 |
|
definition |
The dipropionate ester of a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, beclomethasone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. |
|
Display_Name |
Beclomethasone Dipropionate |
|
FDA_UNII_Code |
5B307S63B2 |
|
Has_Target | ||
in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C176424 |
|
label |
Beclomethasone Dipropionate |
|
Legacy Concept Name |
Beclomethasone |
|
NCI_Drug_Dictionary_ID |
39272 |
|
PDQ_Closed_Trial_Search_ID |
39272 |
|
PDQ_Open_Trial_Search_ID |
39272 |
|
Preferred_Name |
Beclomethasone Dipropionate |
|
prefixIRI |
NCIT:C299 |
|
prefLabel |
Beclomethasone Dipropionate |
|
Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
UMLS_CUI |
C0004906 |
|
subClassOf |