Preferred Name

Beclomethasone Dipropionate

Synonyms
Definitions

The dipropionate ester of a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, beclomethasone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production.

ID

http://purl.obolibrary.org/obo/NCIT_C299

Accepted_Therapeutic_Use_For

Asthma; GI graft vs. host disease, prevention; Nasal polyps; Rhinitis

CAS_Registry

5534-09-8

CHEBI_ID

CHEBI:3002

Chemical_Formula

C28H37ClO7

code

C299

Contributing_Source

CTRP

FDA

HL7

definition

The dipropionate ester of a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, beclomethasone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production.

Display_Name

Beclomethasone Dipropionate

FDA_UNII_Code

5B307S63B2

Has_Target

http://purl.obolibrary.org/obo/NCIT_C17071

in_subset

http://purl.obolibrary.org/obo/NCIT_C63923

http://purl.obolibrary.org/obo/NCIT_C176424

http://purl.obolibrary.org/obo/NCIT_C116977

http://purl.obolibrary.org/obo/NCIT_C116978

label

Beclomethasone Dipropionate

Legacy Concept Name

Beclomethasone

NCI_Drug_Dictionary_ID

39272

PDQ_Closed_Trial_Search_ID

39272

PDQ_Open_Trial_Search_ID

39272

Preferred_Name

Beclomethasone Dipropionate

prefixIRI

NCIT:C299

prefLabel

Beclomethasone Dipropionate

Semantic_Type

Organic Chemical

Pharmacologic Substance

UMLS_CUI

C0004906

subClassOf

http://purl.obolibrary.org/obo/NCIT_C521

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