loading...| Preferred Name |
Triethylenemelamine |
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| Synonyms |
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| Definitions |
A trisaziridine alkylating agent with antineoplastic and carcinogenic properties. Used to induce cancer in experimental animal models, triethylenemelamine ethylates DNA, resulting in inhibition of DNA replication, unscheduled DNA synthesis, chromosomal aberrations, and sister chromatid exchanges. This agent also exhibits reproductive toxicities. (NCI04) |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C29858 |
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| CAS_Registry |
51-18-3 |
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| CHEBI_ID |
CHEBI:27919 |
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| Chemical_Formula |
C9H12N6 |
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| code |
C29858 |
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| Contributing_Source |
FDA |
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| definition |
A trisaziridine alkylating agent with antineoplastic and carcinogenic properties. Used to induce cancer in experimental animal models, triethylenemelamine ethylates DNA, resulting in inhibition of DNA replication, unscheduled DNA synthesis, chromosomal aberrations, and sister chromatid exchanges. This agent also exhibits reproductive toxicities. (NCI04) |
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| FDA_UNII_Code |
F7IY6HZG9D |
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| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C128784 |
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| Is_Value_For_GDC_Property | ||
| label |
Triethylenemelamine |
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| Legacy Concept Name |
Triethylenemelamine |
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| Maps_To |
Triethylenemelamine |
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| NSC Number |
9706 |
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| Preferred_Name |
Triethylenemelamine |
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| prefixIRI |
NCIT:C29858 |
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| prefLabel |
Triethylenemelamine |
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| Semantic_Type |
Pharmacologic Substance |
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| UMLS_CUI |
C0040975 |
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| subClassOf |