Preferred Name

Nicardipine Hydrochloride

Synonyms
Definitions

The hydrochloride salt form of nicardipine, a synthetic derivative of nitrophenyl-pyridine and potent calcium channel blocker, Nicardipine (Nifedipine Family) blocks calcium ions from certain cell walls and inhibits contraction of coronary and peripheral arteries, resulting in lowered oxygen requirements for heart muscle and decreased arterial contraction and spasm. It is used clinically as a cerebral and coronary vasodilator. (NCI04)

ID

http://purl.obolibrary.org/obo/NCIT_C29840

CAS_Registry

54527-84-3

Chemical_Formula

C26H29N3O6.HCl

code

C29840

Contributing_Source

FDA

definition

The hydrochloride salt form of nicardipine, a synthetic derivative of nitrophenyl-pyridine and potent calcium channel blocker, Nicardipine (Nifedipine Family) blocks calcium ions from certain cell walls and inhibits contraction of coronary and peripheral arteries, resulting in lowered oxygen requirements for heart muscle and decreased arterial contraction and spasm. It is used clinically as a cerebral and coronary vasodilator. (NCI04)

FDA_UNII_Code

K5BC5011K3

Has_Free_Acid_Or_Base_Form

http://purl.obolibrary.org/obo/NCIT_C66879

in_subset

http://purl.obolibrary.org/obo/NCIT_C63923

label

Nicardipine Hydrochloride

Legacy Concept Name

Nicardipine

Preferred_Name

Nicardipine Hydrochloride

prefixIRI

NCIT:C29840

prefLabel

Nicardipine Hydrochloride

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0770150

subClassOf

http://purl.obolibrary.org/obo/NCIT_C333

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