Preferred Name

Zaleplon

Synonyms
Definitions

A nonbenzodiazepine from the pyrazolopyrimidine class with hypnotic, sedative, anxiolytic, and muscle relaxant properties. Zaleplon interacts with the gamma-aminobutyric acid (GABA) -A receptor, thereby affecting the chloride channel ionophore complex and potentiating the inhibitory effects of GABA. In addition, zaleplon binds selectively to the brain omega-1 receptor situated on the alpha subunit of the GABA-A/chloride ion channel receptor complex and potentiates t-butyl-bicyclophosphorothionate (TBPS) binding.

ID

http://purl.obolibrary.org/obo/NCIT_C29551

CAS_Registry

151319-34-5

CHEBI_ID

CHEBI:10102

Chemical_Formula

C17H15N5O

code

C29551

Contributing_Source

FDA

definition

A nonbenzodiazepine from the pyrazolopyrimidine class with hypnotic, sedative, anxiolytic, and muscle relaxant properties. Zaleplon interacts with the gamma-aminobutyric acid (GABA) -A receptor, thereby affecting the chloride channel ionophore complex and potentiating the inhibitory effects of GABA. In addition, zaleplon binds selectively to the brain omega-1 receptor situated on the alpha subunit of the GABA-A/chloride ion channel receptor complex and potentiates t-butyl-bicyclophosphorothionate (TBPS) binding.

FDA_UNII_Code

S62U433RMH

in_subset

http://purl.obolibrary.org/obo/NCIT_C63923

label

Zaleplon

Legacy Concept Name

Zaleplon

Preferred_Name

Zaleplon

prefixIRI

NCIT:C29551

prefLabel

Zaleplon

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0251504

subClassOf

http://purl.obolibrary.org/obo/NCIT_C29756

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http://purl.obolibrary.org/obo/CHEBI_10102 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_10102 CHEBI LOOM
http://www.phoc.org.cn/pmo/class/PMO_00026475 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/LNC/LP30650-3 LOINC LOOM
http://www.drugbank.ca/drugs/DB00962 FTC LOOM
http://www.co-ode.org/ontologies/galen#Zaleplon GALEN LOOM
http://purl.bioontology.org/ontology/RXNORM/74667 RXNORM LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000148625 ODAE LOOM
https://go.drugbank.com/drugs/DB00962 MDM LOOM
http://purl.bioontology.org/ontology/MESH/C085665 MESH LOOM
http://purl.bioontology.org/ontology/VANDF/4021177 VANDF LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29551 NCIT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C085665 RH-MESH LOOM
http://purl.bioontology.org/ontology/NDDF/007833 NDDF LOOM
http://purl.bioontology.org/ontology/LNC/MTHU015092 LOINC LOOM
http://purl.bioontology.org/ontology/ATC/N05CF03 ATC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0251504 OCHV LOOM
http://www.semanticweb.org/ftuha/ontologies/2021/5/FRMO-01untitled-ontology-175/Zaleplon_(Sonata) FRMO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#25175 OCHV LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148625 NDFRT LOOM
http://purl.obolibrary.org/obo/CHEBI_10102 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_10102 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_10102 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_10102 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_10102 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_10102 ODNAE LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387012004 SNOMEDCT LOOM